We understand that you are having troubles with your Trend Micro Security as it has been turned off. We are more than happy to help you with this.
We need to clarify what is the exact error message that the notice you received is displaying? Does it say that the Protection is Disabled? Providing a screen shot of the message will be a great help.
Possible causes of this issue are conflicting programs. Can you recall installing any programs or any other antivirus programs in the past days before this happened?