Hello there mrcovert99 ! Welcome to the community. Thanks for posting here.
We understand that you are having troubles with uninstalling a program that you have on your computer. I have checked for possible solutions in removing the Tweakbit program on your computer.
On your keyboard, kindly press and hold the Windows Key and then hit the R button once. The run window should pop up and it will allow you to place a command. Kindly input this command:
This command will open your computer's Programs and Features. Once this Window is open, kindly locate the Tweakbit program and do a double click on it to have it uninstalled. If this does not work, I would suggest that you boot your computer in Safe Mode then try to do the uninstallation from there. Let us know if this works. Trend Micro Home Users Community